INTERNATIONAL CONGRESS OF
PharmacoGenetics
Economic effects on gut microbiome
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Hossein ameri shahrabi,1,*
1. Azad University
- Introduction: Gut microbiota is well recognized as a key determinant of health and disease. Consequently, several studies have focused on the causality and predictive/prognostic value of microbiota in a wide range of diseases. However, understanding what sparks changes in the microbiota and how these changes contribute to increased disease susceptibility is of greater importance. Few studies have shown that gut microbiota can be altered by lifestyle and thus lead to pathology. What if socio-economic factors also affect the composition of the gut microbiota and thus increase susceptibility to disease? Perhaps, this is one of the factors that may have contributed to the increase in inequality between people with higher and lower socio-economic status in terms of health. In this review, we aim to understand more about this issue and the true impact of the biological community. In addition, we proposed criteria to reduce the impact of these factors on the gut microbiota composition.
- Methods: Eradication of poverty is listed as one of the main Millennium Development Goals (MDGs) that must be tackled by the World Health Organization, especially in low-income countries (1). Therefore, it shows that health is a key determinant of increasing socio-economic status and, hence, can affect a person's success throughout life. Therefore, it is important to get the best chance for health at an early age. The microbiota is intrinsically linked to health and disease, making it promising to understand part of the pathophysiology, which, in turn, can help achieve a healthier state, especially given the therapeutic potential to modulate microbiota composition.
- Results: It seems that this trait has a greater impact than heritability on the composition of their microbiota. Thus, childhood interventions on the microbiota can increase an individual's chances of success throughout life, along with improving the country's productivity because the burden of disease will be reduced. In addition, biocommunity can lead to better screening of harms along with increased efficiency through appropriate health policies specifically designed for specific neighborhoods. In summary, investing in personal microbiota interventions in early life, especially in low SE neighborhoods, can induce a win-win situation, where health inequalities are attenuated along with increased overall productivity.
- Conclusion: Microbiota has a great impact on health and disease. As a result, the factors that can form its composition are among the factors affecting a person's health. Therefore, we may understand that society influences health inequalities and can reduce these inequalities. In addition, SES should be considered in microbiota research because it can be an important intervening variable that can affect the interpretation of study results.
- Keywords: Microbiome - Gut - Health - Disease
